RRM
11-25-2002
01:07 PM | too bad that they don't say anything about the opioid peptides in wheat-gluten;
quote:
From this site:
One single wheat-gluten protein-molecule contains 15 samples of one particular opioid peptide. (10) Wheat-gluten also contains a number of extremely powerful opioid peptides (11). Some of these molecules are even 100 times more powerful than a morphine-molecule. (12)
Opioid peptides in wheat-gluten are ;
Glycine-Tyrosine-Tyrosine-Proline (11)
Tyrosine-Glycine-Glycine-Tryptophane (11)
Tyrosine-Proline-Isoleucine-Serine-Leucine (11)
Tyrosine-Glycine-Glycine-Tryptophane-Leucine (13) ,which is the most powerful one.
Tyrosine-Glycine-Glycine- is also the sequence of the first three amino acids in endorphins ; opioid peptides produced by the body, influencing the same receptors in the brain.
Therefore, wheat-opioid peptides can 'sedate' the bowels so much that constipation is caused. (13) Because some wheat-opioids are extremely powerful, some schizophrenics can even be cured by not eating any wheat-products anymore. (14)
(10) Fukudome, S. et al, Release of opioid peptides, gluten exorphins by the action of pancreatic elastase. FEBS Lett. 1997 / 412 (3) / 475-479.
(11) Fukudome, S. et al, Gluten exorphin C : a novel opioid peptide derived from wheat gluten. FEBS Lett. 1993 / 316 (1) / 17-19.
(12) Max ,B., This and that : an artefactual alkaloid and its peptide analogs. Trends Pharmacol. Sci. 1992 / 13 (9) / 341-345.
(13) Fukodome, S. et al, Opioid peptides derived from wheat gluten : their isolation and characterization. FEBS lett. 1992 / 296 (1) / 107-111.
(14) Dohan, F.C. ,Genetics and idiopathic schizophrenia. Am. J. Psychiatry 1989 / 146 (11) / 1522-1523. , Dohan, F.C. ,Genetic hypothesis of idiopathic schizophrenia : its exorphin connection. Schizophr. Bull. 1988 / 14 (4) / 489-494. , Paroli, E. et al, Opioid peptides from food (the exorphins). World Rev. Nutr. Diet. 1988 / 55 / 58-97. , Morley, J.E., Food peptides. A new class of hormones ? J. Am. Med. Assoc. 1982 / 247 (17) / 2379-2380 , Ross-Smith, P. et al, Diet (gluten) and Schizophrenia. J. Hum. Nutr. 1980 / 34 (2) / 107-112.
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Wai
01-29-2003
03:31 PM | quote:
Do any fruits, nuts or seeds contain any of these compounds? (or anything else dangerous in other ways?)
some seeds may, since they contain alkaloids, which is the family to which the opioid peptides belong to. But not fruits / easy to digest nuts.
Seeds and grains not just contain enzyminihibitors, but also alkaloids to scare off animals that what to eat them.
Not all seeds and grains have been investigated regarding the presence of opioid peptides, and also not regarding other alkaloids...
Fruits and eay to digest nuts are safe. |
